BDBM50360177 CHEMBL1929555

SMILES Nc1nc(Nc2ccc(Cl)cc2)c2cc(Cc3cccc4ccccc34)[nH]c2n1

InChI Key InChIKey=XSIGGCHYNXSJBX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50360177   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50360177(CHEMBL1929555)
Affinity DataIC50:  1.26E+4nMAssay Description:Inhibition of EGFR tyrosine kinase activity in EGF-stimulated human A431 cells after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50360177(CHEMBL1929555)
Affinity DataIC50:  8.92E+3nMAssay Description:Inhibition of PDGFRbeta tyrosine kinase activity in PDGF-BB-stimulated human SF-539 cells after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50360177(CHEMBL1929555)
Affinity DataIC50:  3.11E+4nMAssay Description:Inhibition of VEGFR1 tyrosine kinase activity in VEGF-stimulated human A498 cells after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50360177(CHEMBL1929555)
Affinity DataIC50:  620nMAssay Description:Inhibition of VEGFR2 tyrosine kinase activity in VEGF-stimulated human U251 cells after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed