BDBM50364607 CHEMBL1951304

SMILES CCc1cc(CN2CC(C2)C(O)=O)sc1-c1noc(n1)-c1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=DWVJASHDNJMDNH-UHFFFAOYSA-N

Data  9 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50364607   

TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50364607(CHEMBL1951304)
Affinity DataEC50:  4nMAssay Description:Agonist activity at human S1P1 receptor assessed as stimulation of [35S]GTPgamma bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50364607(CHEMBL1951304)
Affinity DataEC50: >2.00E+4nMAssay Description:Agonist activity at human S1P3 receptor assessed as stimulation of [35S]GTPgamma bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50364607(CHEMBL1951304)
Affinity DataEC50:  4nMAssay Description:Agonist activity at human S1P1 receptor expressed in CHO-K1 cells assessed as induction of GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50364607(CHEMBL1951304)
Affinity DataEC50: >2.00E+4nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO-K1 cells assessed as induction of GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50364607(CHEMBL1951304)
Affinity DataEC50: >2.00E+4nMAssay Description:Agonist activity at human S1P3 receptor by [S35]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50364607(CHEMBL1951304)
Affinity DataEC50:  17nMAssay Description:Agonist activity at human S1P5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Rattus norvegicus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50364607(CHEMBL1951304)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at rat S1P1 receptor expressed in CHO-K1 cells assessed as induction of GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50364607(CHEMBL1951304)
Affinity DataEC50:  4nMAssay Description:Agonist activity at human S1P1 receptor by [S35]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 4(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50364607(CHEMBL1951304)
Affinity DataEC50:  58nMAssay Description:Agonist activity at human S1P4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed