BDBM50371215 CHEMBL1162963

SMILES CN(C)c1nc2CCn3cc(C4=C(C(=O)NC4=O)c4cn(CCCc1cc2)c1ccccc41)c1ccccc31

InChI Key InChIKey=ZVYLAQPDMUKXOT-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50371215   

TargetProtein kinase C beta type(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50371215(CHEMBL1162963)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human recombinant PKCbeta2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50371215(CHEMBL1162963)
Affinity DataIC50:  850nMAssay Description:Inhibition of human Rsk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50371215(CHEMBL1162963)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human Rsk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50371215(CHEMBL1162963)
Affinity DataIC50:  98nMAssay Description:Inhibition of human PKCthetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50371215(CHEMBL1162963)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50371215(CHEMBL1162963)
Affinity DataIC50:  510nMAssay Description:Inhibition of human MSK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50371215(CHEMBL1162963)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of human TrkBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50371215(CHEMBL1162963)
Affinity DataIC50:  48nMAssay Description:Inhibition of human Rsk3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed