BDBM50374666 CHEMBL259450

SMILES CCc1ccccc1NC(=O)CSC(=O)NNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C

InChI Key InChIKey=OTIWAYTTYNFEKL-QFIPXVFZSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50374666   

TargetProcathepsin L(Homo sapiens (Human))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50374666(CHEMBL259450)
Affinity DataIC50:  56nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50374666(CHEMBL259450)
Affinity DataIC50:  5.60E+4nMAssay Description:pA2 for NK2 receptor of rabbit pulmonary arteryMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProcathepsin L(Homo sapiens (Human))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50374666(CHEMBL259450)
Affinity DataIC50:  56nMAssay Description:Inhibition of human recombinant Cathepsin L assessed as Kinact using Z-FR-AMC as substrate incubated for 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProcathepsin L(Homo sapiens (Human))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50374666(CHEMBL259450)
Affinity DataIC50:  56nMAssay Description:Inhibition of cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed