BDBM50378955 CHEMBL2011250::US9394290, 19

SMILES N#Cc1cccc(c1)-c1ccc(Cn2ccnc2)cn1

InChI Key InChIKey=FLZCOZXEATXACZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50378955   

TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Universitaet Des Saarlandes Campus Saarbruecken

US Patent
LigandPNGBDBM50378955(CHEMBL2011250 | US9394290, 19)
Affinity DataIC50:  409nMT: 2°CAssay Description:V79MZ cells expressing human CYP11B1 and human CYP11B2 genes, respectively, were grown on 24-well cell culture plates (8×10^5 cells per well) w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50378955(CHEMBL2011250 | US9394290, 19)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Universitaet Des Saarlandes Campus Saarbruecken

US Patent
LigandPNGBDBM50378955(CHEMBL2011250 | US9394290, 19)
Affinity DataIC50:  409nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50378955(CHEMBL2011250 | US9394290, 19)
Affinity DataIC50: >1.00E+3nMT: 2°CAssay Description:V79MZ cells expressing human CYP11B1 and human CYP11B2 genes, respectively, were grown on 24-well cell culture plates (8×10^5 cells per well) w...More data for this Ligand-Target Pair
In DepthDetails US Patent