BDBM50388721 CHEMBL2059862

SMILES Cc1cnc(-c2ccc(C)c(NC(=O)c3ccc(OCc4ccccn4)cc3)c2)n1C

InChI Key InChIKey=ICEFWVJUDOWXTD-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50388721   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50388721(CHEMBL2059862)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50388721(CHEMBL2059862)
Affinity DataEC50:  11nMAssay Description:Inhibition of Smo expressed in mouse C3H10T1/2 cells assessed as reduction in alkaline phosphatase level after 72 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed