BDBM50393216 CHEMBL2151413

SMILES CC(C)n1cc(C2=C(C(=O)NC2=O)c2nc(nc3ccccc23)N2CCN(C)CC2)c2ccccc12

InChI Key InChIKey=JHFLXYPDFJHPMX-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50393216   

TargetProtein kinase C beta type(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50393216(CHEMBL2151413)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of PKCbeta-1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50393216(CHEMBL2151413)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of PKCdelta by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50393216(CHEMBL2151413)
Affinity DataIC50:  11nMAssay Description:Inhibition of PKCalpha by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50393216(CHEMBL2151413)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of PKCtheta by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C eta type(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50393216(CHEMBL2151413)
Affinity DataIC50:  11nMAssay Description:Inhibition of PKCeta by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50393216(CHEMBL2151413)
Affinity DataIC50:  11nMAssay Description:Inhibition of PKCepsilon by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed