BDBM50399457 CHEMBL2179400

SMILES CCCCCCCCCCCCCCCC(=O)OC[C@H](CSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(O)=O)OC(=O)CCCCCCCCCCCCCCC

InChI Key InChIKey=LJUIOEFZFQRWJG-GHYFRYPYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50399457   

TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50399457(CHEMBL2179400)
Affinity DataEC50:  3.70nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as induction of NF-kappaB signaling after 24 hrs by luminescence based luciferase r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTLR2/TLR6(Homo sapiens (Human))
Panjab University

Curated by ChEMBL
LigandPNGBDBM50399457(CHEMBL2179400)
Affinity DataEC50:  0.300nMAssay Description:Agonist activity at human TLR2/TLR6 expressed in HEK-Blue hTLR2-TLR6 cells by SEAP reporter gene based Quanti-blue assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50399457(CHEMBL2179400)
Affinity DataIC50:  426nMAssay Description:Inhibition of biotin labelled Pam2CSK4 binding to His tagged human TLR2 after 45 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 2(Mus musculus)
Keio University

Curated by ChEMBL
LigandPNGBDBM50399457(CHEMBL2179400)
Affinity DataIC50:  349nMAssay Description:Inhibition of biotin labelled Pam2CSK4 binding to mouse TLR2 Fc chimera protein after 45 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed