BDBM50401549 CHEMBL2207081
SMILES Clc1ccc(Cn2ccnn2)c(NS(=O)(=O)c2ccc(Cl)c(Cl)c2)c1
InChI Key InChIKey=YGWURLOZYUXZKA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50401549
Affinity DataKi: 10nMAssay Description:Binding affinity to CCR2 by 35S-gamma-GTP membrane assayMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Binding affinity to human CCR2More data for this Ligand-Target Pair
Affinity DataKi: 79.4nMAssay Description:Antagonist activity at CCR2 assessed as inhibition of CCL2-stimulated THP-1 cell chemotaxis in presence of 0.1% human serumMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Antagonist activity at CCR2 assessed as inhibition of CCL2-stimulated THP-1 cell chemotaxis in presence of 1% human serumMore data for this Ligand-Target Pair
Affinity DataKi: 398nMAssay Description:Binding affinity to CCR1 by 35S-gamma-GTP membrane assayMore data for this Ligand-Target Pair
Affinity DataKi: 398nMAssay Description:Binding affinity to CCR4 by 35S-gamma-GTP membrane assayMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+3nMAssay Description:Binding affinity to murine CCR2More data for this Ligand-Target Pair
Affinity DataIC50: >5.01E+4nMAssay Description:Inhibition of cytochrome P450 2D6More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of cytochrome P450 2C19More data for this Ligand-Target Pair
Affinity DataKd: 1.00E+4nMAssay Description:Antagonist activity at CCR2 in human whole blood assessed as inhibition of CCL2-stimulated monocyte shape changeMore data for this Ligand-Target Pair
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of cytochrome P450 3A4More data for this Ligand-Target Pair
Affinity DataIC50: 631nMAssay Description:Inhibition of cytochrome P450 2C9More data for this Ligand-Target Pair
Affinity DataIC50: >5.01E+4nMAssay Description:Inhibition of cytochrome P450 1A2More data for this Ligand-Target Pair