BDBM50413835 CHEMBL5282046

SMILES CCc1ccc(cc1)N(CC(C)C)S(=O)(=O)c1ccc2OC(CC3CCOCC3)CC(O)c2c1

InChI Key InChIKey=XUGZSZVPACAPNZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50413835   

TargetNuclear receptor ROR-gamma(Human)
Jiangsu Carefree Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50413835(CHEMBL5282046)
Affinity DataIC50: 5nMAssay Description:Displacement of BODIPY from APC-labelled human RORgammat LBD incubated for 15 mins by by LANCE detection analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Jiangsu Carefree Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50413835(CHEMBL5282046)
Affinity DataIC50: 22nMAssay Description:Inhibition of RORgammat in human Jurkat cells assessed as inhibition of RORgammat transcriptional activity incubated for 10 mins by luciferase report...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed