BDBM50417667 CHEMBL1643574
SMILES Nc1nccc2cc(O[C@H]3CCCN(Cc4ccccc4)C3)ccc12
InChI Key InChIKey=IZFFAYAQVHNZHH-IBGZPJMESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50417667
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Msd
Curated by ChEMBL
Msd
Curated by ChEMBL
Affinity DataKi: 794nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: 91.2nMAssay Description:Inhibition of ROCK2 by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 776nMAssay Description:Inhibition of ROCK1 in human THP cells assessed as inhibition of MCP1-induced cell migrationMore data for this Ligand-Target Pair