BDBM50426431 CHEMBL2322362

SMILES Cc1cc(C)c(cc1C(=O)N1CCC(CC1)c1ccc(cc1)C#N)-c1nc2cc(ncc2[nH]1)S(C)(=O)=O

InChI Key InChIKey=POKZTVXFAGESFV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50426431   

TargetFatty acid synthase(Homo sapiens (Human))
3-V Biosciences

US Patent
LigandPNGBDBM50426431(CHEMBL2322362)
Affinity DataIC50:  85nMAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
3-V Biosciences

US Patent
LigandPNGBDBM50426431(CHEMBL2322362)
Affinity DataIC50:  85nMAssay Description:Inhibition of human FASN assessed as release of co-enzyme AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Rattus norvegicus)
3-V Biosciences

Curated by ChEMBL
LigandPNGBDBM50426431(CHEMBL2322362)
Affinity DataIC50:  2.43E+3nMAssay Description:Inhibition of rat FASN assessed as release of co-enzyme AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed