BDBM50426433 CHEMBL2322360
SMILES Cc1cc(C)c(cc1C(=O)N1CCC(CC1)c1ccc(cc1)C#N)-c1nc2cc(ncc2[nH]1)N1CCCC1
InChI Key InChIKey=RQFGSMJAYHTSOT-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50426433
Affinity DataIC50: 22nMAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of rat FASN assessed as release of co-enzyme AMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of FASN in human HeLa cells assessed as reduction of de novo synthesis of palmitateMore data for this Ligand-Target Pair
Affinity DataIC50: 62nMAssay Description:Inhibition of FASN in rat NMU cells assessed as reduction of de novo synthesis of palmitateMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of human FASN assessed as release of co-enzyme AMore data for this Ligand-Target Pair