BDBM50426445 CHEMBL2322372

SMILES O=C(N1CCC(CC1)c1ccc(cc1)C#N)c1cccc(c1)-c1nc2cc(ncc2[nH]1)N1CCCC1

InChI Key InChIKey=GUCACUBJEZUIJZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50426445   

TargetFatty acid synthase(Homo sapiens (Human))
3-V Biosciences

US Patent
LigandPNGBDBM50426445(CHEMBL2322372)
Affinity DataIC50:  130nMAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
3-V Biosciences

US Patent
LigandPNGBDBM50426445(CHEMBL2322372)
Affinity DataIC50:  130nMAssay Description:Inhibition of human FASN assessed as release of co-enzyme AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Rattus norvegicus)
3-V Biosciences

Curated by ChEMBL
LigandPNGBDBM50426445(CHEMBL2322372)
Affinity DataIC50:  2.95E+3nMAssay Description:Inhibition of rat FASN assessed as release of co-enzyme AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed