BDBM50432790 CHEMBL2348796
SMILES C[C@H](Oc1cccc(Cl)c1Cl)C(=O)Nc1ccc2oc(nc2c1)-c1ccncc1
InChI Key InChIKey=HRXGXBGJVNUGSX-LBPRGKRZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50432790
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
National Institute of Allergy and Infectious Diseases
Curated by ChEMBL
National Institute of Allergy and Infectious Diseases
Curated by ChEMBL
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human IMPDH2 using IMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
TargetGMP reductase 2(Homo sapiens)
National Institute of Allergy and Infectious Diseases
Curated by ChEMBL
National Institute of Allergy and Infectious Diseases
Curated by ChEMBL
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human GMPR2 using GMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
National Institute of Allergy and Infectious Diseases
Curated by ChEMBL
National Institute of Allergy and Infectious Diseases
Curated by ChEMBL
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
National Institute of Allergy and Infectious Diseases
Curated by ChEMBL
National Institute of Allergy and Infectious Diseases
Curated by ChEMBL
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of Cryptosporidium IMPDH preincubated for 10 mins before substrate addition by spectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Bacillus anthracis)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of Bacillus anthracis IMPDH preincubated for 10 mins before substrate addition by spectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...More data for this Ligand-Target Pair