BDBM50433168 CHEMBL2377799

SMILES CC(C)(C)c1ccc(CN(Cc2ccc(cc2)C(C)(C)C)S(=O)(=O)C(Cc2ccc(NC(=O)C(O)=O)cc2)c2nc3ccccc3o2)cc1

InChI Key InChIKey=BIUBEXLIOLBQRQ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50433168   

TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50433168(CHEMBL2377799)
Affinity DataKi:  6.40E+3nMAssay Description:Inhibition of TCPTP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50433168(CHEMBL2377799)
Affinity DataKi:  1.49E+4nMAssay Description:Inhibition of PTP1B (unknown origin)-mediated pNPP hydrolysis to 4-nitrophenol after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed