BDBM50444531 CHEMBL3099680

SMILES Oc1ccc(Nc2nc(cs2)-c2ccc(NC(=O)C34CC5CC(CC(C5)C3)C4)cc2)cc1

InChI Key InChIKey=SIJVIZUYHOJMFH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50444531   

TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe University

Curated by ChEMBL
LigandPNGBDBM50444531(CHEMBL3099680)
Affinity DataIC50:  170nMAssay Description:Inhibition of recombinant soluble epoxide hydrolase (unknown origin) using PHOME as substrate incubated 15 mins prior to substrate addition measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Goethe University

Curated by ChEMBL
LigandPNGBDBM50444531(CHEMBL3099680)
Affinity DataIC50:  30nMAssay Description:Inhibition of recombinant 5-lipoxygenase (unknown origin) expressed in Escherichia coli BL21(DE3) using arachidonic acid as substrate incubated for 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed