BDBM50448713 CHEMBL3127876

SMILES OC12CC3CC(C1)C(NC(=O)c1scnc1[C@H]1CCCO1)C(C3)C2

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50448713   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50448713(CHEMBL3127876)
Affinity DataIC50: 10nMAssay Description:Inhibition of N-terminal 6-His-tagged full-length human 11beta-HSD1 assessed as conversion of cortisone to cortisol after 25 mins by competitive HTRF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50448713(CHEMBL3127876)
Affinity DataIC50: 360nMAssay Description:Inhibition of N-terminal 6-His-tagged full-length mouse 11beta-HSD1 assessed as conversion of cortisone to cortisol after 25 mins by competitive HTRF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed