BDBM50451688 CHEMBL4213557

SMILES CC(C)n1c(C)nc2c(F)cc(cc12)-c1cc(Nc2cnc(CN3CCN(CC4CC4)CC3)cn2)ncn1

InChI Key InChIKey=YUTSNVSLGLNUDW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50451688   

TargetCyclin-dependent kinase 6(Human)
Shanghai Haihe Pharmaceutial

Curated by ChEMBL
LigandPNGBDBM50451688(CHEMBL4213557)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of CDK6 (unknown origin) using U-light as substrate preincubated for 1 hr followed by EDTA addition measured after 1 hr by LANCE Ultra kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Shanghai Haihe Pharmaceutial

Curated by ChEMBL
LigandPNGBDBM50451688(CHEMBL4213557)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of CDK4 (unknown origin) using U-light as substrate preincubated for 1 hr followed by EDTA addition measured after 1 hr by LANCE Ultra kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Shanghai Haihe Pharmaceutial

Curated by ChEMBL
LigandPNGBDBM50451688(CHEMBL4213557)
Affinity DataIC50: 103nMAssay Description:Inhibition of CDK1 (unknown origin) using U-light as substrate preincubated for 1 hr followed by EDTA addition measured after 1 hr by LANCE Ultra kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed