BDBM50459572 CHEMBL4216339
SMILES CCn1cc(Nc2nc(N)nc(n2)-c2cccc(c2CO)-n2ccc3cc(cc(F)c3c2=O)C2CC2)cc1C#N
InChI Key InChIKey=YRDMGLSTJWMOGG-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50459572
Affinity DataIC50: 6.30nMAssay Description:Inhibition of N-terminal DYKDDDDK tagged biotinylated activated human recombinant BTK using FITC-labeled Srctide peptide substrate by mobility shift ...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Carna Biosciences
Curated by ChEMBL
Carna Biosciences
Curated by ChEMBL
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells at holding potential of -80 mV by patch clamp methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.580nMAssay Description:Inhibition of N-terminal DYKDDDDK tagged biotinylated unactivated human recombinant BTK using FITC-labeled Srctide peptide substrate by by mobility s...More data for this Ligand-Target Pair