BDBM50459709 CHEMBL4209052::US10836764, Compound 137

SMILES C(C1CCC1)c1ccnc2N3CCNCC3CCc12

InChI Key InChIKey=WDUJNEUBVHIQQH-UHFFFAOYSA-N

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50459709   

Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM50459709(CHEMBL4209052 | US10836764, Compound 137)
Affinity DataKi:  7.90nMAssay Description:Radioligand binding assays were performed using the commercially available 5-HT2 receptor agonist [125I]DOI as the radioligand and nonspecific bindin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM50459709(CHEMBL4209052 | US10836764, Compound 137)
Affinity DataKi:  134nMAssay Description:Radioligand binding assays were performed using the commercially available 5-HT2 receptor agonist [125I]DOI as the radioligand and nonspecific bindin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM50459709(CHEMBL4209052 | US10836764, Compound 137)
Affinity DataKi:  311nMAssay Description:Radioligand binding assays were performed using the commercially available 5-HT2 receptor agonist [125I]DOI as the radioligand and nonspecific bindin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM50459709(CHEMBL4209052 | US10836764, Compound 137)
Affinity DataEC50:  2.51E+3nMAssay Description:Agonist activity at recombinant 5-HT2A receptor (unknown origin) expressed in HEK293 cells assessed as increase in [3H]-inositol phosphate accumulati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM50459709(CHEMBL4209052 | US10836764, Compound 137)
Affinity DataEC50:  4.02E+3nMAssay Description:Agonist activity at recombinant 5-HT2B receptor (unknown origin) expressed in HEK293 cells assessed as increase in [3H]-inositol phosphate accumulati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM50459709(CHEMBL4209052 | US10836764, Compound 137)
Affinity DataEC50:  12nMAssay Description:Agonist activity at recombinant 5-HT2C receptor (unknown origin) expressed in HEK293 cells assessed as increase in [3H]-inositol phosphate accumulati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed