BDBM50463223 CHEMBL4237391

SMILES [O-][N+](=O)c1cccc(Nc2nc(NC3CCNCC3)nc(n2)C#N)c1

InChI Key InChIKey=ZBAFFXDNRIXACA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50463223   

TargetCathepsin S(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50463223(CHEMBL4237391)
Affinity DataIC50: 10nMAssay Description:Inhibition of human cathepsin S using Z-LR-AMC as substrate after 30 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCathepsin K(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50463223(CHEMBL4237391)
Affinity DataIC50: 30nMAssay Description:Inhibition of human cathepsin K using Z-Phe-Arg-AMC as substrate after 30 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50463223(CHEMBL4237391)
Affinity DataIC50: 30nMAssay Description:Inhibition of human cathepsin L using Z-Phe-Arg-AMC as substrate after 30 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCathepsin B(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50463223(CHEMBL4237391)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human cathepsin B using Z-Phe-Arg-AMC as substrate after 30 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed