BDBM50469275 CHEMBL4290673

SMILES Brc1ccc2[nH]cc(\C=N\NC(=O)CC#N)c2c1

InChI Key InChIKey=BEFLZFMWSIYTNW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50469275   

TargetProstaglandin G/H synthase 1(Sheep)
Universidade Federal De Pernambuco (Ufpe)

Curated by ChEMBL
LigandPNGBDBM50469275(CHEMBL4290673)
Affinity DataIC50: 180nMAssay Description:Inhibition of ovine COX-1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Universidade Federal De Pernambuco (Ufpe)

Curated by ChEMBL
LigandPNGBDBM50469275(CHEMBL4290673)
Affinity DataIC50: 250nMAssay Description:Inhibition of recombinant N-terminal His6-tagged human COX-2 expressed in Baculovirus infected Sf21 cells using arachidonic acid as substrate preincu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed