BDBM50479264 Alternariol 5-O-Sulfate::CHEMBL483525

SMILES Cc1cc(O)cc2oc(=O)c3c(O)cc(OS(O)(=O)=O)cc3c12

InChI Key InChIKey=IOBDCMVQCAWFQQ-UHFFFAOYSA-N

Data  24 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 50479264   

TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479264(Alternariol 5-O-Sulfate | CHEMBL483525)
Affinity DataIC50:  1.12E+3nMAssay Description:Inhibition of recombinant SAKMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479264(Alternariol 5-O-Sulfate | CHEMBL483525)
Affinity DataIC50:  2.24E+4nMAssay Description:Inhibition of recombinant METMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479264(Alternariol 5-O-Sulfate | CHEMBL483525)
Affinity DataIC50:  2.06E+3nMAssay Description:Inhibition of recombinant VEGFR2More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479264(Alternariol 5-O-Sulfate | CHEMBL483525)
Affinity DataIC50:  975nMAssay Description:Inhibition of recombinant FLT3More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479264(Alternariol 5-O-Sulfate | CHEMBL483525)
Affinity DataIC50:  2.18E+3nMAssay Description:Inhibition of recombinant B-RAF-V600E mutantMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479264(Alternariol 5-O-Sulfate | CHEMBL483525)
Affinity DataIC50:  2.21E+3nMAssay Description:Inhibition of recombinant ARK5More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479264(Alternariol 5-O-Sulfate | CHEMBL483525)
Affinity DataIC50:  1.24E+4nMAssay Description:Inhibition of recombinant EGFRMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479264(Alternariol 5-O-Sulfate | CHEMBL483525)
Affinity DataIC50:  3.84E+3nMAssay Description:Inhibition of recombinant PDGFRbetaMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479264(Alternariol 5-O-Sulfate | CHEMBL483525)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of recombinant PLK1More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479264(Alternariol 5-O-Sulfate | CHEMBL483525)
Affinity DataIC50:  5.91E+3nMAssay Description:Inhibition of recombinant CK2alpha1More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479264(Alternariol 5-O-Sulfate | CHEMBL483525)
Affinity DataIC50:  5.02E+3nMAssay Description:Inhibition of recombinant VEGFR3More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479264(Alternariol 5-O-Sulfate | CHEMBL483525)
Affinity DataIC50:  8.57E+3nMAssay Description:Inhibition of recombinant INSRMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479264(Alternariol 5-O-Sulfate | CHEMBL483525)
Affinity DataIC50: >2.95E+4nMAssay Description:Inhibition of recombinant AKT1More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479264(Alternariol 5-O-Sulfate | CHEMBL483525)
Affinity DataIC50:  1.65E+4nMAssay Description:Inhibition of recombinant SRCMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 8(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479264(Alternariol 5-O-Sulfate | CHEMBL483525)
Affinity DataIC50:  2.21E+4nMAssay Description:Inhibition of recombinant COTMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479264(Alternariol 5-O-Sulfate | CHEMBL483525)
Affinity DataIC50:  650nMAssay Description:Inhibition of recombinant Aurora BMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479264(Alternariol 5-O-Sulfate | CHEMBL483525)
Affinity DataIC50:  2.48E+3nMAssay Description:Inhibition of recombinant CDK2/CycAMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479264(Alternariol 5-O-Sulfate | CHEMBL483525)
Affinity DataIC50:  7.98E+3nMAssay Description:Inhibition of recombinant CDK4/CycD1More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479264(Alternariol 5-O-Sulfate | CHEMBL483525)
Affinity DataIC50:  1.15E+3nMAssay Description:Inhibition of recombinant Aurora AMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479264(Alternariol 5-O-Sulfate | CHEMBL483525)
Affinity DataIC50:  2.48E+4nMAssay Description:Inhibition of recombinant ERBB2More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479264(Alternariol 5-O-Sulfate | CHEMBL483525)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of recombinant FAKMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479264(Alternariol 5-O-Sulfate | CHEMBL483525)
Affinity DataIC50:  2.01E+4nMAssay Description:Inhibition of recombinant TIE2More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479264(Alternariol 5-O-Sulfate | CHEMBL483525)
Affinity DataIC50:  1.44E+4nMAssay Description:Inhibition of recombinant IGF1RMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479264(Alternariol 5-O-Sulfate | CHEMBL483525)
Affinity DataIC50:  9.16E+3nMAssay Description:Inhibition of recombinant EPHB4More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed