BDBM50482314 CHEMBL1171404

SMILES Cc1cc(cc(C)c1Oc1nc(NC2CCN(Cc3ccc(cc3Cl)C#N)CC2)ncc1Br)C#N

InChI Key InChIKey=ZDAFGILEEKZUGC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50482314   

TargetReverse transcriptase(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482314(CHEMBL1171404)
Affinity DataIC50:  146nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482314(CHEMBL1171404)
Affinity DataIC50:  159nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed