BDBM50483311 CHEBI:75458::CHEMBL457504::Carbonyl Cyanide P-Trifluoromethoxyphenyl Hydrazone

SMILES FC(F)(F)[#8]-c1ccc(-[#7]\[#7]=[#6](\C#N)C#N)cc1

InChI Key InChIKey=BMZRVOVNUMQTIN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50483311   

TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50483311(CHEBI:75458 | CHEMBL457504 | Carbonyl Cyanide P-Tr...)
Affinity DataIC50:  510nMAssay Description:Inhibition of hypoxia-induced HIF1 activation in human T47D cells by HRE3-TK-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50483311(CHEBI:75458 | CHEMBL457504 | Carbonyl Cyanide P-Tr...)
Affinity DataIC50:  310nMAssay Description:Inhibition of 1, 10-phenanthroline-induced HIF1 activation in human T47D cells by HRE3-TK-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed