BDBM50490557 CHEMBL2338396

SMILES [H][C@]12CC[C@]([H])(C[C@H](C1)c1nc3c(cnn3c3[nH]nc(C)c13)-c1ccc(nc1)-c1ccccc1)N2C(=O)c1nnc[nH]1

InChI Key InChIKey=BUOZDMLNVZSXNY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50490557   

TargetTarget of rapamycin complex subunit LST8(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50490557(CHEMBL2338396)
Affinity DataIC50: 100nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as reduction in phosphorylated 4E-BP1Thr37/46 level after 90 mins by immunofluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed