BDBM50491761 CHEMBL2385573
SMILES OC(=O)Cc1ccc(Nc2nc(nc3CCCSc23)-c2ccccc2)cc1
InChI Key InChIKey=IUDNSMYYWXWADB-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50491761
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of human recombinant PDE4B (152 to 564 amino acids) using cAMP as substrate after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of full-length human PDE4D2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of recombinant human PDE4D (78 to 508)More data for this Ligand-Target Pair