BDBM50495404 CHEMBL3110289
SMILES COc1ccc2c(CCNC(=O)c3cc(=O)c4c(OCc5ccc(Br)cc5)cccc4o3)c[nH]c2c1
InChI Key InChIKey=CDVAZDPJSYGNKQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50495404
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Bmssi Umr 5086 Cnrs/Universit£
Curated by ChEMBL
Bmssi Umr 5086 Cnrs/Universit£
Curated by ChEMBL
Affinity DataEC50: 80nMAssay Description:Inhibition of ABCG2-mediated mitoxantrone efflux in mitoxantrone-selected human H460 cells after 30 mins by flow cytometric analysisMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Bmssi Umr 5086 Cnrs/Universit£
Curated by ChEMBL
Bmssi Umr 5086 Cnrs/Universit£
Curated by ChEMBL
Affinity DataEC50: 1.00E+8nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed in HEK293 cells assessed as increase in mitoxantrone accumulation incubated for 30 mins by flow cytome...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Bmssi Umr 5086 Cnrs/Universit£
Curated by ChEMBL
Bmssi Umr 5086 Cnrs/Universit£
Curated by ChEMBL
Affinity DataEC50: 100nMAssay Description:Inhibition of ABCG2 (unknown origin)-mediated mitoxantrone efflux expressed in HEK293 cells after 30 mins by flow cytometric analysisMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Bmssi Umr 5086 Cnrs/Universit£
Curated by ChEMBL
Bmssi Umr 5086 Cnrs/Universit£
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of human ABCG2 expressed in Sf9 insect cell membranes assessed as inhibition of quercetin-stimulated ATPase activity after 30 mins by colo...More data for this Ligand-Target Pair