BDBM50495779 CHEMBL3114953

SMILES COc1ccc(cc1F)-c1nc2CCCS(=O)(=O)c2c(Nc2cc(F)c(CC(O)=O)cc2Cl)n1

InChI Key InChIKey=LEDMOHCRKNDGPJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50495779   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50495779(CHEMBL3114953)
Affinity DataIC50:  9.90nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50495779(CHEMBL3114953)
Affinity DataIC50:  560nMAssay Description:Inhibition of full-length human PDE4D2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed