BDBM50499587 CHEMBL3739527

SMILES C[S+]([O-])c1ccc(\C=C2\C(C)=C(CC(=O)OCCOc3cc4ncnc(Nc5cccc(c5)C#C)c4cc3OCCOC(=O)CC3=C(C)\C(=C\c4ccc(cc4)[S+](C)[O-])c4ccc(F)cc34)c3cc(F)ccc23)cc1

InChI Key InChIKey=PALXYTXSYLZDRR-AGTSVBGFSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50499587   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Guangzhou Institutes of Biomedicine and Health

Curated by ChEMBL
LigandPNGBDBM50499587(CHEMBL3739527)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human COX-2 preincubated for 15 mins by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Guangzhou Institutes of Biomedicine and Health

Curated by ChEMBL
LigandPNGBDBM50499587(CHEMBL3739527)
Affinity DataIC50:  27nMAssay Description:Inhibition of EGFR (unknown origin) using tyrosine 4 as substrate by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Guangzhou Institutes of Biomedicine and Health

Curated by ChEMBL
LigandPNGBDBM50499587(CHEMBL3739527)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Ovine COX-1 preincubated for 15 mins by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed