BDBM50500982 CHEMBL3798147

SMILES COc1cc(C)c(CNCC(NC(=O)c2cc(C)on2)c2ccc(cc2)C#CCO)cc1C

InChI Key InChIKey=DNHSLHQHJBUNLI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50500982   

TargetSphingosine-1-phosphate lyase 1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50500982(CHEMBL3798147)
Affinity DataIC50: 150nMAssay Description:Inhibition of human sphingosine 1-phosphate lyase after 22 hrs by umbelliferone fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50500982(CHEMBL3798147)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of wild-type full-length human sphingosine 1-phosphate lyase transfected in HEK293-H cells preincubated for 30 mins followed by addition o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed