BDBM50500983 CHEMBL3798874

SMILES Cc1cc(no1)C(=O)NC(CNCc1cc(C)c(OCC(F)(F)F)cc1C)c1ccccc1

InChI Key InChIKey=HLXDPVXTEBHJTE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50500983   

TargetSphingosine-1-phosphate lyase 1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50500983(CHEMBL3798874)
Affinity DataIC50: 240nMAssay Description:Inhibition of wild-type full-length human sphingosine 1-phosphate lyase transfected in HEK293-H cells preincubated for 30 mins followed by addition o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50500983(CHEMBL3798874)
Affinity DataIC50: 590nMAssay Description:Inhibition of human sphingosine 1-phosphate lyase after 22 hrs by umbelliferone fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed