BDBM50503139 CHEMBL1242115

SMILES CC(C)n1nc(-c2cccc(c2)C(=O)NC2=NCCS2)c2c(N)ncnc12

InChI Key InChIKey=WGYPOAXANMFHMT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50503139   

TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503139(CHEMBL1242115)
Affinity DataIC50:  80nMAssay Description:Inhibition of mTORC2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))TBA
LigandPNGBDBM50503139(CHEMBL1242115)
Affinity DataIC50:  80nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))TBA
LigandPNGBDBM50503139(CHEMBL1242115)
Affinity DataIC50:  80nMAssay Description:Inhibition of recombinant mTOR (unknown origin) using 4EBP1 as substrate in presence of [gamma-32P]ATP by radiometric scintillation assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTarget of rapamycin complex subunit LST8(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503139(CHEMBL1242115)
Affinity DataIC50:  8nMAssay Description:Inhibition of mTORC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed