BDBM50503775 CHEMBL4439909
SMILES Cc1cc(cc(C)c1S(N)(=O)=O)N1CC(CC1=O)C(O)=O
InChI Key InChIKey=LYVVRBXEBODTED-UHFFFAOYSA-N
Data 33 Kd
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 33 hits for monomerid = 50503775
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Kaunas University of Technology
Curated by ChEMBL
Kaunas University of Technology
Curated by ChEMBL
Affinity DataKd: 0.270nMAssay Description:Binding affinity to recombinant full length N-terminal His6x-tagged human CA5B expressed in Escherichia coli Rosetta 2 (DE3) assessed as intrinsic di...More data for this Ligand-Target Pair
Affinity DataKd: 0.0590nMAssay Description:Inhibition of human recombinant CA14 assessed as intrinsic dissociation constant by thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.00E+4nMAssay Description:Binding affinity to recombinant human CA7 by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.230nMAssay Description:Binding affinity to recombinant human CA9 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 3nMAssay Description:Binding affinity to recombinant human CA1 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.890nMAssay Description:Binding affinity to recombinant human CA2 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.270nMAssay Description:Binding affinity to recombinant human CA4 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Kaunas University of Technology
Curated by ChEMBL
Kaunas University of Technology
Curated by ChEMBL
Affinity DataKd: 0.460nMAssay Description:Binding affinity to recombinant full length C-terminal His6x-tagged human CA5A expressed in Escherichia coli BL21(DE3) assessed as intrinsic dissocia...More data for this Ligand-Target Pair
Affinity DataKd: 3.20E+3nMAssay Description:Binding affinity to recombinant N-terminal His6x-tagged human CA14 (20 to 280 residues) catalytic domain expressed in Escherichia coli Rosetta 2 (DE3...More data for this Ligand-Target Pair
Affinity DataKd: 1.20E+4nMAssay Description:Binding affinity to recombinant human CA2 by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Kaunas University of Technology
Curated by ChEMBL
Kaunas University of Technology
Curated by ChEMBL
Affinity DataKd: 8.30E+3nMAssay Description:Binding affinity to recombinant full length C-terminal His6x-tagged human CA5A expressed in Escherichia coli BL21(DE3) by DSF-based fluorescence ther...More data for this Ligand-Target Pair
Affinity DataKd: 2.00E+4nMAssay Description:Binding affinity to recombinant human CA1 by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 5.90E+3nMAssay Description:Binding affinity to recombinant human CA4 by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Kaunas University of Technology
Curated by ChEMBL
Kaunas University of Technology
Curated by ChEMBL
Affinity DataKd: 3.30E+3nMAssay Description:Binding affinity to recombinant full length N-terminal His6x-tagged human CA5B expressed in Escherichia coli Rosetta 2 (DE3) by DSF-based fluorescenc...More data for this Ligand-Target Pair
Affinity DataKd: 2.50E+4nMAssay Description:Binding affinity to recombinant human CA6 by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.20nMAssay Description:Binding affinity to recombinant human CA13 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.0590nMAssay Description:Binding affinity to recombinant N-terminal His6x-tagged human CA14 (20 to 280 residues) catalytic domain expressed in Escherichia coli Rosetta 2 (DE3...More data for this Ligand-Target Pair
Affinity DataKd: 0.370nMAssay Description:Binding affinity to recombinant human CA6 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 8.30E+3nMAssay Description:Binding affinity to recombinant human CA13 by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.30nMAssay Description:Binding affinity to recombinant human CA7 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.490nMAssay Description:Binding affinity to recombinant human CA12 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 7.70E+3nMAssay Description:Binding affinity to recombinant human CA12 by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 3nMAssay Description:Inhibition of human recombinant CA1 assessed as intrinsic dissociation constant by thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.890nMAssay Description:Inhibition of human recombinant CA2 assessed as intrinsic dissociation constant by thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.270nMAssay Description:Inhibition of human recombinant CA4 assessed as intrinsic dissociation constant by thermal shift assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Kaunas University of Technology
Curated by ChEMBL
Kaunas University of Technology
Curated by ChEMBL
Affinity DataKd: 0.460nMAssay Description:Inhibition of human recombinant CA5A assessed as intrinsic dissociation constant by thermal shift assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Kaunas University of Technology
Curated by ChEMBL
Kaunas University of Technology
Curated by ChEMBL
Affinity DataKd: 0.270nMAssay Description:Inhibition of human recombinant CA5B assessed as intrinsic dissociation constant by thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.370nMAssay Description:Inhibition of human recombinant CA6 assessed as intrinsic dissociation constant by thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.30nMAssay Description:Inhibition of human recombinant CA7 assessed as intrinsic dissociation constant by thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.230nMAssay Description:Inhibition of human recombinant CA9 assessed as intrinsic dissociation constant by thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.490nMAssay Description:Inhibition of human recombinant CA12 assessed as intrinsic dissociation constant by thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.20nMAssay Description:Inhibition of human recombinant CA13 assessed as intrinsic dissociation constant by thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 5.00E+3nMAssay Description:Binding affinity to recombinant human CA9 by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair