BDBM50503789 CHEMBL4452277
SMILES Cc1cc(N2CC(CC2=O)C(O)=O)c(Cl)c(C)c1S(N)(=O)=O
InChI Key InChIKey=PXKOFARYUUHCAL-UHFFFAOYSA-N
Data 31 Kd
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 31 hits for monomerid = 50503789
Affinity DataKd: 33nMAssay Description:Binding affinity to recombinant N-terminal His6x-tagged human CA3 (4 to 260 residues) expressed in Escherichia coli BL21(DE3) assessed as intrinsic d...More data for this Ligand-Target Pair
Affinity DataKd: 0.25nMAssay Description:Inhibition of human recombinant CA13 assessed as intrinsic dissociation constant by thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 4.30E+3nMAssay Description:Binding affinity to recombinant human CA1 by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 360nMAssay Description:Binding affinity to recombinant human CA4 by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.0270nMAssay Description:Binding affinity to recombinant human CA7 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 697nMAssay Description:Binding affinity to recombinant human CA2 in pH 7 sodium phosphate buffer at 37 degC by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 5nMAssay Description:Binding affinity to recombinant human CA1 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.120nMAssay Description:Binding affinity to recombinant human CA2 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.130nMAssay Description:Binding affinity to recombinant human CA4 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.710nMAssay Description:Binding affinity to recombinant human CA6 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 290nMAssay Description:Binding affinity to recombinant human CA9 by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.30E+3nMAssay Description:Binding affinity to recombinant human CA12 by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 220nMAssay Description:Binding affinity to recombinant human CA13 by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Kaunas University of Technology
Curated by ChEMBL
Kaunas University of Technology
Curated by ChEMBL
Affinity DataKd: 530nMAssay Description:Binding affinity to recombinant full length N-terminal His6x-tagged human CA5B expressed in Escherichia coli Rosetta 2 (DE3) by DSF-based fluorescenc...More data for this Ligand-Target Pair
Affinity DataKd: 56nMAssay Description:Binding affinity to recombinant human CA7 by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.600nMAssay Description:Binding affinity to recombinant human CA12 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 6.30E+3nMAssay Description:Binding affinity to recombinant human CA6 by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 220nMAssay Description:Binding affinity to recombinant human CA2 by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.10E+5nMAssay Description:Binding affinity to recombinant N-terminal His6x-tagged human CA3 (4 to 260 residues) expressed in Escherichia coli BL21(DE3) by DSF-based fluorescen...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Kaunas University of Technology
Curated by ChEMBL
Kaunas University of Technology
Curated by ChEMBL
Affinity DataKd: 0.330nMAssay Description:Binding affinity to recombinant full length N-terminal His6x-tagged human CA5B expressed in Escherichia coli Rosetta 2 (DE3) assessed as intrinsic di...More data for this Ligand-Target Pair
Affinity DataKd: 0.100nMAssay Description:Binding affinity to recombinant human CA9 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 5nMAssay Description:Inhibition of human recombinant CA1 assessed as intrinsic dissociation constant by thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.120nMAssay Description:Inhibition of human recombinant CA2 assessed as intrinsic dissociation constant by thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 33nMAssay Description:Inhibition of human recombinant CA3 assessed as intrinsic dissociation constant by thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.130nMAssay Description:Inhibition of human recombinant CA4 assessed as intrinsic dissociation constant by thermal shift assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Kaunas University of Technology
Curated by ChEMBL
Kaunas University of Technology
Curated by ChEMBL
Affinity DataKd: 0.330nMAssay Description:Inhibition of human recombinant CA5B assessed as intrinsic dissociation constant by thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.710nMAssay Description:Inhibition of human recombinant CA6 assessed as intrinsic dissociation constant by thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.0270nMAssay Description:Inhibition of human recombinant CA7 assessed as intrinsic dissociation constant by thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.100nMAssay Description:Inhibition of human recombinant CA9 assessed as intrinsic dissociation constant by thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.600nMAssay Description:Inhibition of human recombinant CA12 assessed as intrinsic dissociation constant by thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.25nMAssay Description:Binding affinity to recombinant human CA13 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair