BDBM50505506 CHEMBL3431191

SMILES CC(=O)Nc1ccc(cc1)-c1noc(CC2CCCN(Cc3cccc(F)c3C)C2)n1

InChI Key InChIKey=XFSYGJBPBTWLFR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50505506   

TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50505506(CHEMBL3431191)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of N-terminal His6 tagged human sirtuin 2 (25 to 389 residues) using Cbz-Lys(acetyl)-AMC as substrate after 4 hrs in presence of NAD+ by h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase(Schistosoma mansoni)
University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50505506(CHEMBL3431191)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of recombinant Schistosoma mansoni sirtuin 2 (21 to 322 residues) expressed in Escherichia coli BL21(DE3) cells using ZMAL as substrate af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed