BDBM50506675 CHEMBL4565376

SMILES COc1ccc(cc1)-c1csc(n1)N1N=C(CC1c1ccccc1O)c1ccccc1

InChI Key InChIKey=LDVODOMCSBPUEX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50506675   

Target72 kDa type IV collagenase(Human)
Nanjing Agricultural University

Curated by ChEMBL
LigandPNGBDBM50506675(CHEMBL4565376)
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of recombinant human MMP-2 preincubated for 10 mins followed by Mca-PLGL-Dpa-AR-NH2 substrate addition and measured for 5 mins by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Nanjing Agricultural University

Curated by ChEMBL
LigandPNGBDBM50506675(CHEMBL4565376)
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of recombinant human MMP-2 preincubated for 10 mins followed by Mca-PLGL-Dpa-AR-NH2 substrate addition and measured for 5 mins by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Nanjing Agricultural University

Curated by ChEMBL
LigandPNGBDBM50506675(CHEMBL4565376)
Affinity DataIC50: 4.89E+4nMAssay Description:Inhibition of recombinant human MMP-8 using Mca-PLGL-Dpa-AR-NH2 as substrate preincubated for 10 mins followed by substrate addition and measured for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed