BDBM50506811 CHEMBL4578377

SMILES Cc1c(C)c(=O)oc2cc(OCC3CCN(Cc4cccc(OCCCO[N+]([O-])=O)c4)CC3)ccc12

InChI Key InChIKey=XOEFPFRIFYUXTJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50506811   

TargetAcetylcholinesterase(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50506811(CHEMBL4578377)
Affinity DataIC50: 480nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50506811(CHEMBL4578377)
Affinity DataIC50: 550nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected insect cell microsomes using kynuramine as substrate measured after 30 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50506811(CHEMBL4578377)
Affinity DataIC50: 800nMAssay Description:Inhibition of human serum BuChE using butyrylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50506811(CHEMBL4578377)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected insect cell microsomes using kynuramine as substrate measured after 30 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed