BDBM50507150 CHEMBL4440114
SMILES CC(=O)C1=C(O)C=C2Oc3c(c(O)c(C)c(O)c3-c3csc(N\N=C\c4ccc(Cl)cc4)n3)[C@@]2(C)C1=O
InChI Key InChIKey=HEQJGPDVMZFJMO-CXEQAMIMSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50507150
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch of The Russian Academy of Sciences
Curated by ChEMBL
Siberian Branch of The Russian Academy of Sciences
Curated by ChEMBL
Affinity DataKd: 9.46E+3nMAssay Description:Binding affinity to recombinant human Tdp1 (149 to 608 residues) expressed in Escherichia coli BL21 (DE3) by tryptophan fluorescence quenching assayMore data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch of The Russian Academy of Sciences
Curated by ChEMBL
Siberian Branch of The Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 68nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21 (DE3) using 5'-(5,6 FAM-aac gtc agg gtc ttc...More data for this Ligand-Target Pair