BDBM50508274 CHEMBL4436625

SMILES CN1CC[C@H]1CCc1ccc(C)cc1NC(=O)Nc1cccc(Oc2ccc3nc[nH]c(=O)c3c2)c1

InChI Key InChIKey=XOJDIWXWTPTASS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50508274   

TargetSerine/threonine-protein kinase B-raf(Human)
University of South China

Curated by ChEMBL
LigandPNGBDBM50508274(CHEMBL4436625)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of recombinant human GST-fused B-Raf V600E mutant using MEK1 as substrate measured after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed