BDBM50508276 CHEMBL4464237

SMILES Oc1ncnc2c(ccc(Nc3ccc(NC(=O)Nc4cc(ccc4Cl)C(F)(F)F)cc3)c12)[N+]([O-])=O

InChI Key InChIKey=JOUMFIHFVFJARJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50508276   

TargetVascular endothelial growth factor receptor 2(Human)
University of South China

Curated by ChEMBL
LigandPNGBDBM50508276(CHEMBL4464237)
Affinity DataIC50: 12nMAssay Description:Inhibition of VEGFR2 (unknown origin) using FAM-labelled peptide as substrate measured after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of South China

Curated by ChEMBL
LigandPNGBDBM50508276(CHEMBL4464237)
Affinity DataIC50: 15nMAssay Description:Inhibition of VEGFR2 (unknown origin) using poly (Glu,Tyr) 4:1 as substrate measured after 1 hr in presence of ATP by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed