BDBM50508278 CHEMBL4578561

SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(Cl)c(F)c3)c2cc1NC(=O)\C=C\CN(C)C

InChI Key InChIKey=QZPMWLDKXQPVRC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50508278   

TargetEpidermal growth factor receptor(Human)
University of South China

Curated by ChEMBL
LigandPNGBDBM50508278(CHEMBL4578561)
Affinity DataIC50: 39nMAssay Description:Inhibition of recombinant human His6-tagged EGFR cytoplasmic domain (645 to 1186 residues) expressed in baculovirus infected Sf9 insect cells assesse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
University of South China

Curated by ChEMBL
LigandPNGBDBM50508278(CHEMBL4578561)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of VEGFR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed