BDBM50508766 CHEMBL4437689::US11091474, Example 1

SMILES COCCC(Cc1c[nH]c2ccccc12)NC(=O)c1cnc(s1)N1CCN(C)CC1

InChI Key InChIKey=PVTFNEPWBMESNF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50508766   

TargetAlpha-synuclein(Human)
Ucb Biopharma

US Patent
LigandPNGBDBM50508766(CHEMBL4437689 | US11091474, Example 1)
Affinity DataIC50: 3.70E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetAlpha-synuclein(Human)
Ucb Biopharma

US Patent
LigandPNGBDBM50508766(CHEMBL4437689 | US11091474, Example 1)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of alpha-synuclein (unknown origin) self-aggregation by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed