BDBM50511354 CHEMBL4444608::US10988478, Example 118

SMILES CC1(C)Cc2cc(NC(=O)c3cnn4cccnc34)c(cc2S1(=O)=O)N1CCOCC1

InChI Key InChIKey=KGZBQSSWOPHRBK-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50511354   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM50511354(CHEMBL4444608 | US10988478, Example 118)
Affinity DataKi:  14nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM50511354(CHEMBL4444608 | US10988478, Example 118)
Affinity DataKi:  14nMAssay Description:Inhibition of recombinant full-length N-terminal His6-tagged human IRAK4 expressed in baculovirus expression system using H-KKARFSRFAGSSPSQSSMVAR pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed