BDBM50512472 CHEMBL4435536

SMILES C(Cc1ccc2[nH]nc(-c3ccc(nc3)N3CCNCC3)c2c1)c1ccccc1

InChI Key InChIKey=MPLREUAIPISHOE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50512472   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50512472(CHEMBL4435536)
Affinity DataIC50:  18nMAssay Description:Inhibition of human GST-tagged TRKA (436 to 790) expressed in baculovirus expression system using TK-biotin peptide as substrate incubated for 45 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50512472(CHEMBL4435536)
Affinity DataIC50: >300nMAssay Description:Antagonist activity at prolink-tagged full length human TrkA expressed in U2OS cells assessed as inhibition of NGF-induced receptor phosphorylation b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed