BDBM50512585 CHEMBL4445276

SMILES CONC(=O)Cc1ccc(cc1)C1(COC1)NC(=O)c1cc2c(Cl)c(Cl)ccc2n1C

InChI Key InChIKey=PLXFEKXUZHVCCT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50512585   

TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Meyer Cancer Center

Curated by ChEMBL
LigandPNGBDBM50512585(CHEMBL4445276)
Affinity DataIC50:  287nMAssay Description:Inhibition of PHGDH (unknown origin) using 140 nM of PHGDH and 3-PG as substrate incubated for 20 mins in presence of NAD+, PSAT1, PSPH by diaphorase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed