BDBM50513123 CHEMBL4576877

SMILES FC(F)(F)C[C@@H](c1cccs1)c1c([nH]c2cc(ccc12)C#N)-c1ccccc1

InChI Key InChIKey=ZQTJTBWIFLKGEE-KRWDZBQOSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50513123   

TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Aberdeen

Curated by ChEMBL
LigandPNGBDBM50513123(CHEMBL4576877)
Affinity DataEC50:  17nMAssay Description:Positive allosteric modulation of human Gi/Go-coupled CB1 receptor expressed in CHOK1 cells assessed as increase in CP55940-induced inhibition of for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Aberdeen

Curated by ChEMBL
LigandPNGBDBM50513123(CHEMBL4576877)
Affinity DataEC50:  828nMAssay Description:Agonist activity at human CB1 receptor expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 30 mins by PathHunt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Aberdeen

Curated by ChEMBL
LigandPNGBDBM50513123(CHEMBL4576877)
Affinity DataEC50:  29nMAssay Description:Agonist activity at human Gi/Go-coupled CB1 receptor expressed in CHOK1 cells assessed as inhibition of forskolin-stimulated cAMP production measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Aberdeen

Curated by ChEMBL
LigandPNGBDBM50513123(CHEMBL4576877)
Affinity DataEC50:  363nMAssay Description:Positive allosteric modulation of human CB1 receptor expressed in CHOK1 cells assessed as increase in CP55940-induced beta-arrestin recruitment prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed