BDBM50513131 CHEMBL4582487

SMILES FC(F)(F)C[C@H](c1cccs1)c1c([nH]c2cc(ccc12)C#N)-c1ccccc1

InChI Key InChIKey=ZQTJTBWIFLKGEE-QGZVFWFLSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50513131   

TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Aberdeen

Curated by ChEMBL
LigandPNGBDBM50513131(CHEMBL4582487)
Affinity DataEC50:  1.21E+3nMAssay Description:Agonist activity at human CB1 receptor expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 30 mins by PathHunt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Aberdeen

Curated by ChEMBL
LigandPNGBDBM50513131(CHEMBL4582487)
Affinity DataEC50:  76nMAssay Description:Agonist activity at human Gi/Go-coupled CB1 receptor expressed in CHOK1 cells assessed as inhibition of forskolin-stimulated cAMP production measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Aberdeen

Curated by ChEMBL
LigandPNGBDBM50513131(CHEMBL4582487)
Affinity DataEC50:  40nMAssay Description:Positive allosteric modulation of human Gi/Go-coupled CB1 receptor expressed in CHOK1 cells assessed as increase in CP55940-induced inhibition of for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Aberdeen

Curated by ChEMBL
LigandPNGBDBM50513131(CHEMBL4582487)
Affinity DataEC50:  342nMAssay Description:Positive allosteric modulation of human CB1 receptor expressed in CHOK1 cells assessed as increase in CP55940-induced beta-arrestin recruitment prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed