BDBM50514591 CHEMBL4577573

SMILES CN1CCN(CCc2nnc(o2)-c2cnc3ccc(cn23)-c2cnc(Cl)c(NS(=O)(=O)c3ccc(F)cc3F)c2)CC1

InChI Key InChIKey=DVNAZSXISSZXHH-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50514591   

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
East China Normal University

Curated by ChEMBL

LigandBDBM50514591(CHEMBL4577573)Copy SMILESCopy InChI

Affinity DataIC50: 0.230nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/21/2021
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL